A case-control study of burning mouth syndrome and sleep dysfunction.
Source
Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, USA. [email protected]
Abstract
OBJECTIVE:
The objective of this study was to evaluate whether sleep dysfunction is a risk factor for burning mouth syndrome (BMS).
STUDY DESIGN:
An age- and sex-matched case-control study of patients with BMS and controls with various oral conditions was conducted. A numerical rating scale for oral discomfort and the sleep scale from the medical outcomes study were used for measurements, and statistical analyses included use of logistic regression models.
RESULTS:
The odds ratios for lowest versus highest quartiles were sleep disturbance (OR = 9.7, P = .0095), sleep problems index (SLP)6 (OR = 7.5, P = .032), and SLP9 (OR = 27, P = .0058), which remained significant after controlling for age and number of sedating medications.
CONCLUSIONS:
Findings from this cross-sectional study, although unable to establish a causal relationship, demonstrate that patients with BMS report a greater degree of sleep problems as compared with controls, and suggest that sleep dysfunction may be a risk factor for BMS and a possible target for treatment.
Copyright © 2011 Mosby, Inc. All rights reserved.
- PMID:
21684770
[PubMed – indexed for MEDLINE]